Waxy Monkey Leaf Frog Defense Mechanism Is Toxic
Waxy Monkey Leaf Frog has a defense mechanism where the amphibian is known for its waxy poisonous substance which is observe on their skin. If the amphibian is stressed or injury it will result in the secretion of the granular gland substances onto the surface of the skin (Chen, Walker, Zhou and Shaw 105) On the surface of the amphibian skin a potent opioid hepta-peptide known as Dermorphin is secreted.
The potency of Dermorphin is 40 times more potent than morphine. The peptide had no substantial antagonistic properties to morphine. However, Naloxone was a potent antagonist of Dermorphin. This is due to administering a low dose of naloxone to the central nervous system and peripheral nervous system (Broccardo, M. et al. 1981). In Figure 1, it demonstrates when a group of mouse and guinea-pig is electrically stimulated and then given an intravenous injection of the peptide. As a result, the dose-response relationship for Dermorphin is more effective with its potency and analgesic activity in the given organism than other peptides.
Waxy Monkey Leaf Frog has a defense mechanism where the amphibian is known for its waxy poisonous substance which is observe on their skin. If the amphibian is stressed or injury it will result in the secretion of the granular gland substances onto the surface of the skin (Chen, Walker, Zhou and Shaw 105) On the surface of the amphibian skin a potent opioid hepta-peptide known as Dermorphin is secreted.
The potency of Dermorphin is 40 times more potent than morphine. The peptide had no substantial antagonistic properties to morphine. However, Naloxone was a potent antagonist of Dermorphin. This is due to administering a low dose of naloxone to the central nervous system and peripheral nervous system (Broccardo, M. et al. 1981). In Figure 1, it demonstrates when a group of mouse and guinea-pig is electrically stimulated and then given an intravenous injection of the peptide. As a result, the dose-response relationship for Dermorphin is more effective with its potency and analgesic activity in the given organism than other peptides.
(Broccardo, M. et al. 1981)
Current Research for Cancer Treatment
Scientists have discovered proteins in frog skins which could be used to treat cancer, diabetes, and stroke and transplant patients by regulating the growth of blood vessels (“Scientist Unlocks Potential of Frog Skin To Treat Cancer” 2) Angiogenesis is known as the growth of blood vessels. This is when cancer tumor cells is growing and is in need of oxygen and nutrients to continue to grow and spread. As a result, the cells will develop their own supply of blood if it is not readily available to them (Niu, Gang, and Xiaoyuan 2).
Scientists have discovered proteins in frog skins which could be used to treat cancer, diabetes, and stroke and transplant patients by regulating the growth of blood vessels (“Scientist Unlocks Potential of Frog Skin To Treat Cancer” 2) Angiogenesis is known as the growth of blood vessels. This is when cancer tumor cells is growing and is in need of oxygen and nutrients to continue to grow and spread. As a result, the cells will develop their own supply of blood if it is not readily available to them (Niu, Gang, and Xiaoyuan 2).